En dan moet je weten dat het coronavirus eigenlijk niet zo heel veel muteert in vergelijking met bijvoorbeeld de griep. Unfortunately, it remains untouched by those who have the power to act. He claims that its because theres so much coronavirus circulating and so many people might produce suboptimal levels of antibody to the virus that, as is the case when antibiotics are used at levels too low to eliminate bacteria and thereby result in strong evolutionary selection for resistant strains of bacteria, a mass vaccination program is doomed to result in resistant variants of coronavirus, particularly when the vaccination program has started out targeted: As if this was not already heavily compromising innate immune defense in this population segment, there comes yet another force into play that will dramatically enhance morbidity and mortality rates in the younger age groups: MASS VACCINATION of the ELDERLY. If we, human beings, are committed to perpetuating our species, we have no choice lef [sic] but to eradicate these highly infectious viral variants. Dat laatste standpunt wordt ook door een klein deel van de wetenschappelijke experts gehuldigd. "There can be no doubt," Vanden Bossche asserts, "that lack of exposure due to stringent containment measures implemented as of the beginning of the pandemic has not been beneficial to keeping peoples innate immune system well trained. (I note that Dr. Vanden Bossche only set up his Twitter account two weeks ago and already has over 16K followers.) That. (Indeed, thus far, it appears that this is the case.) The ongoing phase 3 trial of an adenovirus-vectored spike-based vaccine (Johnson & Johnson, NCT04505722) in South Africa, where the 501Y.V2 (B.1.351) strain with the Glu484Lys substitution is rapidly replacing pre-existing variants,11 might provide an opportunity to examine this question. By educating these cells in ways that enable them to durably recognize and target Coronavirus-infected cells, our immune system could be perfectly armed for a targeted atack to the universe of Coronaviruses prior to exposure. Hes also conflating innate immune responses with specific immune responses induced by either infection or vaccination. Some of you might have seen it already published elsewhere (although this is an edited/abridged version of the original post). David Gorski / March 18, 2021 One benefit of several current COVID-19 vaccines, most notably the mRNA vaccines, is that they can be easily modified to induce the development of antibodies programmed specifically to deal with whatever new variants crop up. Hij beweert dat je door veel te vaccineren tijdens een pandemie een nieuwe en veel dodelijkere vorm van het virus kan creren. Its a rationale for developing reformulated booster vaccines that cover variants not well covered by the currently-used COVID-19 vaccines. Check out pictures, bibliography, biography and community discussions about Geert Vanden Bossche Een vaccin zet je immuunsysteem aan het werk, dat op zijn beurt het virus te lijf zal gaan. Vanden Bossche's scientific argument in broad terms is that the current COVID-19 vaccines, through a mechanism analogous to antibiotic resistance, will create mutant variants of the virus that escape the protection of those vaccines. Nog volgens hem zou zon nieuwe en dodelijkere variant geholpen kunnen worden doordat het coronavaccin ons aangeboren immuunsysteem zou verzwakken. While Vanden Bossche's ideas may be rooted in actual scientific concepts, his argument quite explicitly relies on sweeping assumptions. Dan vraag ik me af waar we mee bezig zijn. More recently, he set up his own website to publicize his letter: We've put together a website to gather all information, scientific documents and interviews I've posted on this public health emergency. It has been observed that over time Mareks disease virus has become more virulent, and this has been attributed classically to a leaky vaccine effect. Noting how quickly Dr. Vanden Bossches letter was embraced by antivaxxers, Frei then writes: But from my experience as a former long-time medical writer and journalist (1988-2016) particularly a four-month stint with media-relations giant FleishmanHillard in 1994 (yes, Ive worked for the dark side) this has all the hallmarks of a drug-company astroturf campaign. Wat beweert hij nu precies en wat is er van aan? He is no stranger to vaccines. Its been accompanied by a video interview posted towhere else?antivaxxer Robert F. Kennedy, Jr.s Childrens Health Defense website. "The underlying fallacy," Omer explained, is that a natural infection is better than a vaccine. And Dr. Vanden Bossches concerns are based on Science! Dit om een bepaalde sfeer te scheppen. CC BY-NC-ND 2.0. Unless I am scientifically proven wrong, it is difficult to understand how current human interventions will prevent circulating variants from turning into a wild monster. Hij wordt op YouTube voorgesteld als een wereldwijde vaccinautoriteit met een grote reputatie, maar dat klopt niet. This problem will be exacerbated, he claims, because people who have been vaccinated (and/or social distancing and staying inside during the pandemic) will be less capable of fighting off those strains than someone who has not been vaccinated. His argument sounds a lot like an argument Andrew Wakefield once made for MMR. Honderdduizenden mensen zagen zijn boodschap intussen. This is what COVID-19 vaccines do, and their ability to reduce the opportunities for the virus to mutate is why rapid vaccination is imperative. Thus if evidence emerges that particular variants do appear to influence vaccine efficacy, it should be possible to periodically reformulate the vaccines so that they better match the circulating strains. Mrz mit einem offenen Brief an die WHO gewandt. Daarna werkte hij als Senior Program Officer voor de Bill & Melinda Gates Foundation en als Senior Ebola Program Manager voor de Global Alliance for Vaccines and Immunization (GAVI). Fact-checkers noemt Vanden Bossche marionetten van een georkestreerde smaadcampagne die zich als leek willen mengen in zulk complex gegeven als virologie. Even so, concern about immune escape is one reason why Pfizer, BioNTech, and Moderna used the entire SARS-CoV-2 spike protein, rather than specific segments of it that might serve as antigens, so that the polyclonal antibody immune response generated would be broad and unlikely to be escaped with single mutationsor even multiple mutations. Movies. This is an absurdly counterproductive solution if Vanden Bossche were truly concerned about variants. Het onderzoek ernaar is nog zeer pril. Hij benoemt dat als een mogelijk risico. In the case of antibiotics, its called developing antibiotic resistance; in the case of vaccines, its called immune escape. National Center for Complementary and Integrative Health, Steven P. Novella, MD Founder and Executive Editor, David H. Gorski, MD, PhD Managing Editor, allowing infection and natural herd immunity to occur is better, American Association of Physicians and Surgeons, The Sixth Extinction: Vaccine Immunity and Measles Mutants in a Virgin Soil, excellent rebuttal of Dr. Vanden Bossches mangling of immunology, proofreading mechanism that results in a low mutation rate, Andrew Wakefield wrote about MMR and vaccines, Nirenbergs demolition of Dr. Vanden Bossches nonsense, The Not-So-Hidden Agenda Behind Bossches Concern Over COVID Mass Vaccination, surgical oncologist at the Barbara Ann Karmanos Cancer Institute, American College of Surgeons Committee on Cancer Liaison Physician, Ear Acupuncture for Procedural Pain in Neonates: More Randomized Controlled Nonsense. Deze website maakt gebruik van cookies. Ook de theorie achter zijn betoog klopt niet: een vaccin onderdrukt het aangeboren immuunsysteem niet, en onvolledig gevaccineerde mensen helpen een virus niet om te veranderen. Hes arguing that vaccinating the elderly protects them, but because the virus will therefore be forced to infect the young it will only be able to do so if it can somehow escape immunity to the antibodies to spike protein (S-specific Abs) transiently raised in asymptomatic subjects. Het gaat ook om een therapeutisch vaccin. Very interested in spirituality. As a result, Im posting this. They shall only be contradicted by science. He also states that hes worked with GAVI: The Vaccine Alliance and the Bill and Melinda Gates Foundation, although searching the websites, I could find no reference to him other than a report written by him and others to GAVI about progress on an Ebola vaccine. Ik ben onafhankelijk en neutraal, heb geen aandelen bij vaccin fabrikanten en ben niet gebonden aan contracten die bepalen wat ik al dan niet mag zeggen. In deze video legt immunoloog Hans-Willem Snoeck uit waarom het voor een virus zeer moeilijk is om bestand te worden tegen een vaccin (lees eronder voort): Ook volgens Favoreel snijdt de stelling van Vanden Bossche geen hout. As the unprecedented extent of human intervention in the Covid-19- pandemic is now at risk of resulting in a global catastrophe without equal, this call cannot sound loudly and strongly enough. Integendeel, de uitbraken zijn onder controle gebracht.. Follow More from Medium Mehek Kapoor in. The production of targeted antibodies obviously creates a different response than a natural infection because "you're producing antibodies against specific needs therefore you have a limited targeted immune response, not the whole response that you see after an infection." De vier wetenschappers die we contacteerden, begrijpen niet hoe daar ook maar iets van zou kunnen kloppen. Hoe schandalig is het brugpensioen van Marc Leemans? Hij was daarbij kritisch over de veiligheid van een ebolavaccin. As I like to say, if you ever write anything that channels Andrew Wakefield, you really should reconsider your life choices. Geert Vanden Bossche is een Belgische dierenarts, viroloog en onafhankelijk onderzoeker en adviseur op het gebied van vaccins. This brings us to our topic, a misinformation-filled open letter by a scientist named Geert Vanden Bossche that went viral over the weekend. (He bases this on the observation that in those infected with COVID-19 asymptomatically, S-specific Ab levels decline faster than in those with symptomatic infections.) It means either "from the woods" or "from Den Bosch ". 1499-1505), Flemish painter. Geert Vanden Bossche - PhD, DVM - Independent | LinkedIn Dr. Vanden Bossche received his DVM from the University of Ghent, Belgium, and his PhD degree in Virology from the University of. 39. 1. Is het levensgevaarlijk om massaal te vaccineren tijdens een epidemie, zoals Vanden Bossche zegt? One answer is, why not? Duitsland blokkeert goedkeuring, Auto rijdt binnen in huis in Mol, bestuurder pleegt vluchtmisdrijf. Even if it were evolving resistance, once again, the answer would be to reformulate the vaccine in order to include the altered antigens, the same conclusion made when considering the possibility that B. pertussis was evolving resistance or that evolutionary drift was leading to the predominance of strains not covered by the vaccine. But, he said, Vanden Bossche's arguments "take a little bit of truth and then add a whole lot of misrepresentation.". Dat is net de aangeboren respons die aangewakkerd wordt., Virussen die resistent worden tegen vaccins, zien we amper. Dit artikel werd gepdatet op 1/4/2021 om 9:26. However, NK cell-based vaccines will primarily enable our natural immunity to be better prepared (memory!) Why? I will note that it is truly astounding how many statements that a supposed expert in immunology and vaccines can make that are just plain out-and-out wrong. Geert Vanden Bossche is known for Compleetdenkers (2022) and Mdia info cit TV (2020). Vanden Bossche stelt het voor alsof een virus na slechts enkele mutaties al bestand kan zijn tegen een vaccin en zo erg dodelijk kan worden. Several variations of the originally isolated strain have emerged since the start of the pandemic, and some of these variants are more infectious, contagious, or possibly deadly. Because, among other things: 1) Neither in the original March 6 piece nor his March 13 follow-up does Vanden Bossche provide any direct, non-theoretical evidence that this is happening; 2) The natural antibodies that are produced after encountering a pathogen are only a small part of a quick, effective and broad-based first-line immune-system defense known as innate or passive immunity which in fact largely comprises other components; and 3) Vanden Bossche downplays the effectiveness of the antibodies our bodies naturally produce as part of the second-line (adaptive) part of the immune system that also has served us extremely well for millennia. Archeologen tonen verborgen gang die ze ontdekten in 4.500 jaar oude piramide van Cheops in Egypte, Het kraakpaleis werd ontruimd, terwijl het een mogelijk alternatief biedt, Open brief: Boos op onze politieke leiders. Wij staken ons licht op bij verschillende vakgenoten en hun oordeel over zijn stelling is eensluidend: Technische nonsens. On March 6, 2021, a Belgian veterinarian named Geert Vanden Bossche published an open letter"to all authorities, scientists and experts around the world" asserting that, in his expert analysis, the current global COVID-19 vaccination program will "wipe out large parts of our human population." Come to think of it, the similarities between Dr. Vanden Bossche and Andrew Wakefield strike me as stronger than ever now, given that, as well documented by Brian Deer, Wakefield basically published his fraudulent science to support the claim that the MMR vaccine causes autism in order to make a market for his own single vaccine against the measles. Claims that Belgium has the best fries in the world! Je laten vaccineren lijkt wel het nieuwe dopen. GEERT VANDEN BOSSCHE: 'MY FINAL CALL' The Highwire with Del Bigtree News Lockdowns Expand in China; Details of New 'Disinformation Czar'; New #PfizerDocuments Released; Geert Vanden Bossche's Final, Dire Warning to the World Guest: Geert Vanden Bossche, DVM, PhD #VandenBossche #GVBFinalCall Episode Website More Episodes Dr. Vanden Bossche has also taken to social media to air his concerns, and his message has been enthusiastically embraced by antivaxxers: Lets just say this. This particular coronavirus happens to have a proofreading mechanism that results in a low mutation rate compared to that of a lot of other RNA viruses, such as, for example, the influenza virus. This new type of vaccines harnesses the power of the immune system by unlocking the untapped potential of self-centered Natural Killer (NK) cells capable of recognising these unconventional antigens. One such claim that I hadnt yet seen is another favorite antivax claim, although admittedly its a rather niche claim in that you dont hear it too often. He even entitled his nonsensical screed The Sixth Extinction: Vaccine Immunity and Measles Mutants in a Virgin Soil. Zie het als een kopieermachine, legt immunoloog Hans-Willem Snoeck (Columbia University, New York)op zijn beurt uit. De experten zitten op twitter fact-checkers te liken en roepen mij op aan de juiste kant te staan. And so am I. I searched PubMed for what I expected to be an extensive publication record on vaccines and foundeight publications, the most recent of which was from 1994 and none of which have anything to do with vaccines. So its not surprising that Dr. Vanden Bossches letter reminds me of Andrew Wakefields warning about the MMR vaccine. Mutations occur during viral transmission and in the bodies of unvaccinated people. So, as we grow up, we increasingly mount pathogen-specific immunity, including highly specific Abs. "There is a sound scientific rationale to assume," Vanden Bossche wrote, "that it is possible to prime NK cells" in ways for them to recognize and kill Coronaviruses at large (including all their variants) at an early stage of infection." Nu is het een ander verhaal. Vanden Bossche has created a scientific-sounding argument that vaccination will encourage the production of COVID-19 variants that our immune systems will be unprepared to fight. Relatiedeskundige Rika Ponnet beantwoordt de vraag van de week: "Moeder-dochterrelaties zijn meest complexe relaties Dan toch geen Europees verbod op benzine- en dieselwagens? Volgens de immunologen die we spraken, is het echt niet zo gemakkelijk om die natural killer-cellen gericht te laten optreden tegen n besmetting, bijvoorbeeld met een vaccin tegen het coronavirus. De community ruimte is een vrije online ruimte (blog) waar vrijwilligers en organisaties hun opinies kunnen publiceren. Jul 4, 2022. Feb 18 Replying to @RespectingFA My intention was to write a scientific work to provide my fellow scientists with the indispensable insight that they now so often lack. En wat doen we ondertussen dan?
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